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Journal of Biomedical Science

Important safety considerations: Patients should call 999 or go to A&E immediately if they experience symptoms of severe allergic reaction such as difficulty breathing, significant swelling of the face or throat, or chest tightness

A 2024 pharmaceutical review in Pharmaceuticals raised concerns that VEGF and VEGFR2 pathway activation in patients with undetected cancers presents a plausible, though unconfirmed, oncological risk